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Project Information
Project Title
Development of a Tetracycline-Loaded Resorbable Membrane for Sustained Local Drug Delivery in Periodontitis
Activity Type
Research Assistant
Program Model
Plan A: GLIP
Eligibility: Exclusively for undergraduate or Master's degree students.
Duration: 1 semester or 3–4 months (depending on the international student's academic calendar)
University Financial Support:
- Tuition fees and other university fees
- On-campus accommodation fees (excluding electricity charges)
- Daily allowance for international students (240 Baht/day)
Eligibility: Exclusively for undergraduate or Master's degree students.
Duration: 1 semester or 3–4 months (depending on the international student's academic calendar)
University Financial Support:
- Tuition fees and other university fees
- On-campus accommodation fees (excluding electricity charges)
- Daily allowance for international students (240 Baht/day)
Duration
May 2027 - August 2027 (4 months)
Applicant Qualifications and Eligibility Requirements:
- Student Status: Applicants must maintain active student status at their home institution throughout the entire duration of the exchange program.
- Program Commitment & Return Requirements: Applicants must complete the full duration of the program and return to their home country on or before the official program end date, in strict compliance with immigration regulations.
- Scholarship Agreement: Applicants must acknowledge, accept, and comply with all rules, terms, and conditions of the scholarship.
- Overseas Health Insurance: Applicants must possess comprehensive overseas medical and health insurance coverage from their home country throughout their study, research, or training period in Thailand. The insurance benefits must explicitly cover sickness, injury, hospitalization expenses (both In-Patient and Out-Patient), medical and rescuer's expenses, personal liability, and death.
- Personal Financial Responsibility: Applicants must accept sole responsibility for all costs and expenses beyond the specified scholarship coverage.
- Schedule & Attendance for Course-Based Programs: For applicants enrolling in Course-Based Programs (Type: Registering in relevant courses), full-semester participation is required (November 16, 2026 – March 21, 2027). Participants must arrive at Naresuan University on November 12, 2026, and depart no later than March 22, 2027. Any changes to arrival or departure dates strictly require prior approval from the program coordinator and the university. (Note: For Internship and Research Assistantship programs, the duration and travel schedule will follow the specific timeline designated for each project).
Additional Project Qualifications:
-Master’s student in Pharmaceutical Sciences, Pharmacy, Biomedical Sciences, Biomaterials, or related fields.
-Basic knowledge of pharmaceutical formulation, drug delivery systems, or biomaterials.
-Basic laboratory skills and ability to conduct experimental research.
-Good command of English for communication and scientific activities.
-Strong interest in drug delivery and periodontal applications.
-Basic knowledge of pharmaceutical formulation, drug delivery systems, or biomaterials.
-Basic laboratory skills and ability to conduct experimental research.
-Good command of English for communication and scientific activities.
-Strong interest in drug delivery and periodontal applications.
Project Status
Open
Activity Details
Overview
This four-month research project offers an opportunity to contribute to the development of an innovative tetracycline-loaded resorbable membrane for sustained local drug delivery in periodontitis. The project integrates pharmaceutical formulation, biomaterials, and periodontal drug delivery, with the goal of improving localized and sustained antimicrobial therapy at the periodontal site. Students will gain hands-on experience in formulation development and optimization, physicochemical and mechanical characterization, mucoadhesion, drug content analysis, in vitro drug release, and stability evaluation. Through active participation in research, data analysis, and scientific presentation, students will strengthen their research skills while engaging in international academic and cultural exchange at Naresuan University.
Weekly Plan
| Week | Activity |
|---|---|
| Week 1 | Orientation and familiarization with Naresuan University, the Faculty of Pharmaceutical Sciences, research facilities, accommodation, and Phitsanulok; laboratory safety training and introduction to the research project. |
| Week 2 | Development and optimization of tetracycline-loaded resorbable membranes with different polymer compositions and drug concentrations, followed by selection of the optimized formulation. |
| Week 3 | Development and optimization of tetracycline-loaded resorbable membranes with different polymer compositions and drug concentrations, followed by selection of the optimized formulation. (Cont.) |
| Week 4 | Development and optimization of tetracycline-loaded resorbable membranes with different polymer compositions and drug concentrations, followed by selection of the optimized formulation. (Cont.) |
| Week 5 | Physicochemical characterization of the developed membranes, including thickness, weight uniformity, surface pH, and morphology using Scanning Electron Microscopy (SEM). |
| Week 6 | Physicochemical characterization of the developed membranes, including thickness, weight uniformity, surface pH, and morphology using Scanning Electron Microscopy (SEM). (Cont.) |
| Week 7 | Evaluation of mechanical properties using puncture testing. |
| Week 8 | Evaluation of in vitro mucoadhesive residence time using mucin-coated cellophane. |
| Week 9 | Evaluation of swelling behavior and in vitro degradation of the optimized membrane under simulated oral conditions. |
| Week 10 | Determination of tetracycline content and drug content uniformity. |
| Week 11 | In vitro tetracycline release study under simulated physiological conditions. |
| Week 12 | In vitro tetracycline release study under simulated physiological conditions. (Cont.) |
| Week 13 | Analysis of drug release profiles and release kinetics. |
| Week 14 | Preliminary stability evaluation and completion of remaining experimental work. |
| Week 15 | Statistical analysis, interpretation of experimental results, and preparation and presentation of the final research report. |
| Week 16 | Cultural activities, local sightseeing, and cultural exchange in Phitsanulok and nearby areas. |
Project Manager
Full Name (EN)
Nattakanwadee Khumpirapang
Faculty / Institute
Faculty of Pharmaceutical Sciences
Email
nattakanwadeek@nu.ac.th